Very complex techniques in Adobe Photoshop, or plugin software that will allow for very fast, and great looking results, Even as a professional, I always (and I mean always) use plug in software to help me reduce noise, or even remove it all together, This is my Imagenomic Noiseware Review. When you have an image with noise from a High ISO that you need to remove, you have two choices.
It does not matter if it's a $150 point and shoot, or a $5000 Professional DSLR.
Any time you want to take an indoor picture, your camera will either manually, or automatically, raise the ISO.